Magnetic Resonance Angiography and Perfusion (MRAP)
Drs. Gulani, Muzic and Griswold are developing a new technique called Magnetic Resonance Angiography and Perfusion (MRAP), in which time-resolved MR angiography (trMRA) data are used also to obtain quantitative perfusion measurements, providing a comprehensive evaluation of both small and large vessel pathologies in a single MR exam. With this unique dual use of the data, high quality, high resolution angiography and perfusion exams are obtained in a single setting, while also saving the patient a dose of contrast. MRAP has been successfully applied in the leg, with accurate and repeatable measurements that can measure changes in muscle physiology (exercise related perfusion changes). They hope to apply this method to evaluate peripheral arterial disease in the near future. Initial experiments in the kidneys are encouraging, and efforts are underway to extend the method also to liver imaging.