Secondary Appointments

 

Education

  • PhD  Swiss Federal Institute of Technology, Zurich, Switzerland
  • B.S. Nankai University, China.

Research Summary

 

Awards and Honors

 

Publications

 

Wang C, Wu C, Zhu J, Miller R.H, Wang YM, Design, Synthesis and Evaluation of Coumarin-based Molecular Probes for Imaging of Myelination, Journal of Medicinal Chemistry, in press (2011).

Wang C, Wu C, Popescu D, Zhu J, Macklin W, Miller R.H, Wang YM, Longitudinal Optical Imaging of Myelination Based on Near Infrared Fluorescence, Journal of Neuroscience 31(7):2382-2390 (2011)

Frullano L, Wang C, Miller, RH, Wang YM, A Myelin-Specific MR-Contrast Agent for Imaging of Myelination, Journal of American Chemical Society, 133(6): 1611–1613 (2011)

Wu C, Tang Z, Fan W, Zhu W, Wang C, Somoza E, Owino N, Li R, Ma PC, Wang YM, Radiosynthesis and Evaluation of [11C]SU11274 for In Vivo PET Imaging of MET Receptors, J. Med. Chem., 53(1), 139-146, 2010. 

Salem N, Kuang Y, Corn D, Erokwu B, Kolthammer JA, Tian H, Wu C, Wang F, Wang YM, Lee Z, [(Methyl)1-11C]-Acetate Metabolism in Hepatocellular Carcinoma, Mol Imaging Biol, , in press, 2010

Wang C, Popescu D, Wu C, Zhu J, Macklin W, Wang YM, In Situ Fluorescence Imaging of Myelination, J. Histochem. Cytochem., 58(7), 611-621, 2010

Spring-Robinson C, Chandramouli V, Schumann WC, Faulhaber PF, Wang YM, Wu C-Y, Faramarz I-B, Muzic RF Jr. , Uptake of [18F]6FDG by Skeletal Muscle is Responsive to Insulin Stimulation, J. Nucl. Med., 50, 912-919, 2009

Wang, YM, Wu C, Caprariello A.V, Somoza E, Zhu W, Wang C, Miller R. H, Quantification of Myelin Changes in the Vertebrate Nervous System, J. Neurosci., 29(46), 14663-14669, 2009

Wang YM, Liu L, Wu C, Alina B, Somoza E, Zhu W, Gerson SL, Direct Quanification of Abasic Site for In Vivo Studies of DNA Damage and Repair, Nucl. Med. Biol., 36, 975-983, 2009

Wu C-Y, Wei J-J, Tian D-H, Feng Y, Miller R.H, Wang YM, Molecular Probes for Imaging Myelinated White Matter in CNS, J. Med. Chem., 51(21), 6682-6688, 2008

Tang Z, Du R, Jiang S, Wu C, Barkauskas DS, Richey J, Molter J, Lam M, Flask C, Gerson S, Dowlati A, Liu L, Halmos B, Lee Z, Wang YM, Kern JA, Ma PC , Optimized MET Targeted Inhibition as Treatment Strategy for EGFR Inhibitor-Resistant Lung Cancer, Br. J. Cancer, 99, 911-922, 2008

Wu C, Wei J, Gao K, Wang YM, Dibenzothiazoles as Novel Amyloid Imaging Agents, Bioorg. Med. Chem., 15, 2789-2796, 2007

Wu, Chunying, Cai, L., Wei, J., Pike, VW, Wang, YM, Lipophilic Analogs of Thioflavin S as Novel Amyloid-Imaging Agents, Curr Alzheimer Res, 3, 259-266, 2006

Wu C, Tian D, Feng Y, Polak P, Wei JJ, Sharp A, Stankoff B, Lubetzki C, Zalc B, Mufson EJ, Gould RM, Feinstein DL, Wang YM, A Novel Myelin Probe that Readily Enter the Brain and Selectively Binds to Meylin Sheaths, J. Histochem. Cytochem., 54, 997 - 1004, 2006

Stankoff B, Wang YM, Bottlaender M, Aigrot M-S, Dolle F, Wu C, Feinstein DL, Huang GF, Semah F, Mathis CA, Klunk WE, Gould RM, Lubetzki C, Zalc B, Imaging of CNS myelin by positrons emission tomography (PET), Proc. Natl. Acad. Sci. U.S.A., 103, 9304-9309, 2006

Wei JJ, Wu CY, Lankin D, Gulrati A, Valyi-Nagy T, Cochran E, Pike VW, Kozikowski A, Wang YM, Development of Novel Amyloid Imaging Agents Based Upon Thioflavin S, Curr Alzheimer Res, 2109-114, 109-114, 2005

Wu CY, Pike VW, Wang YM, Amyloid Imaging –From Bench to Bedside, Curr. Top. Dev. Biol., 70, 171-213, 2005

Klunk WE, Engler H, Nordberg A, Wang YM, Blomqvist G, Bergström M, Holt DP, Bergstrom, Huang GF, Estrada S, Debnath ML, Barletta J, Price, J, Sandell J, Lopresti B, Wall A, Antoni G, Mathis CA, Långström B, Amyloid-imaging with the carbon-11 Labeled benzothiazole, PIB, in Alzheimer patients and controls, Ann. Neurol., 55, 306- 319, 2004

Mathis, CA, Wang, YM, Klunk WE, Imaging of Amyloid-β Plaques and Neurofibrillary Tangles in Aging Human Brain, Curr. Pharm. Des., 10, 1469-1492, 2004

Wang YM, Klunk WE, Debnath ML, Huang GF, Holt DP, Shao L., Mathis CA, Development of A PET/SPECT Agent for Amyloid Imaging in Alzheimer’s Disease, J. Mol. Neurosci., 24, 61-68, 2004


 

 

Email
yanming.wang@case.edu
 
Phone
216-844-3288
Fax
216-844-8062
 
Mailing Address
11100 Euclid Avenue
Bolwell Building Room S109
Cleveland, OH 44106
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