Ohio University - Aerial and Commercial Photography

      Research Summary

      Mr. Molter's interest is in the various forms optical imaging (Photomicrography, chemi-luminescence, fluorescence and gross photography). He has developed a technique to image live cells using bioluminescence while they are in a micro-incubator environment. He also developed an electronic phantom in conjunction with Jefferson National Labs to assess the spectral sensitivity of many different bioluminescent platforms. He pioneered a simple technique to deal with false luminescent signals coming from the GI tract in mice. These findings were presented at the WMIC in 2008 in Nice, France.

      He has worked on numerous projects for CWRU researchers and outside companies involving optical imaging. Mr. Molter has worked with bioluminescence since 2004, introducing many researchers to this field of molecular imaging. He also works with X-ray, CT, SPECT, Cryo-imaging and Fluorescence.

      Click on the link to the right for the Case Center for Imaging Research facilities. You will see the various imaging modalities available for pre-clinical imaging research.

      Patent: 5,813,984
      Forensic Skull and Soft Tissue Database on On-line Facial Reconstruction of Victims and Age Progression Portrait Rendering of Missing Children Through Utilization of Advanced Diagnostic Radiologic Modalities.


      Molter, J, Alfidi R. Improved Lighting Techniques for Reproducing Radiographs on 35-mm Rapid -Process Copy Film. Radiology, (140)1:243, July 1981

      Photographic consultant and production for Computed Tomography of the Whole Body, by John Haaga, M.D. published in 1983, reprinted and updated in 1987, 1994, 2002 and 2008. C. V. Mosby Co. New York, N.Y.

      Love Z, Dennis J, Wang F, Molter J, Lin Y, Auletta J, Weisenberger A, Majewski S, Gerson, S, Lee, Z. Multimodal imaging of mesenchymal stem cell transplant. J Nucl Med 2006; 47(Supplement 1):100P

      Salem N, Schomisch S, Kuang Y, Anderson P, Molter J, Wang F, Tennant B, O’Donnell J, Lee, Z. Comparison of 11C-acetate, 11C-choline, 6FDG and 2FDG for imaging hepatocellular carcinoma in the woodchuck model. J Nucl Med 2006; 47(Supplement 1):177P

      Lin Y, Molter J, Lee Z, Gerson S. Bioluminescence imaging of hematopoietic stem cell repopulation in murine models. Methods Mol Biol 2008;430:295-306.

      Tang Z, Du R, Jiang S, Barkauskas D, Richey J, Molter J, Lam M, Flask C, Gerson S, Dowlati A, Liu L, Lee Z, Halmos B, Wang Y, Kern JA, Ma PC. Dual MET-EGFR combinatorial inhibition against  T790M-EGFR mediated erlotinib resistant lung cancer. Br J Cancer 2008 Sep;99(6):911-922.

      Wang F, Dennis JE, Awadallah A, Solchaga LA, Molter J, Kuang Y, Salem N, Lin Y, Tian H, Kolthammer JA, Kim Y, Love ZB, Gerson SL, Lee Z. Transcriptional profiling of human mesenchymal stem cells transduced with reporter genes for imaging. Physiol Genomics 2009 Mar 3;37(1):23-34.

      Li,W, Lu, Banerjee S, Zhong J, Ye A, Molter J, Yu, X. Ex vivo diffusion tensor MRI reflects microscopic structural remodeling associated with aging and disease progression in normal and cardiomyopathic Syrian hamsters. NMR in Biomed. 2009; 22: 1-7

      Yurek DM, Fletcher AM, Smith GM, Seroogy KB, Ziady AG, Molter J, Kowalczyk TH, Padegimas L, Cooper MJ. Long term transgene expression in the central nervous system using DNA nanoparticles. Mol Ther 2009 Apr;17(4):641-50.

      Lu X, Guo H, Molter J, Gerber L, Barnes EL, Vogel H, Lee Z, Luo G, Wang B Alpha-fetoprotein-thymidine kinase-luciferase knockin mice: A novel model for dual modality longitudinal imaging of tumorigenesis in liver. J Hepatol. 2011 Jul;(55)1):96-102

        Mailing Address
        Department of Radiology
        University Hospitals Case Medical Center
        11100 Euclid Avenue
        Cleveland, Ohio 44106
         Wearn B41

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